To investigate the components of the cardiac Bcl-2 family survival pathway in the coexistence of hypertension and ovariectomy, we measured the protein levels of Bcl-2, Bcl-xL and p-Bad in the left ventricles excised from the WKY, SHR-Sham and SHR-OVX groups by Western blotting. This evidence concerns the gene BAD and hypertensive disorder.