TCF7L2 and type 2 diabetes mellitus: Even though the TCF7L2-rs7903146 polymorphism was significantly associated with a higher T2D prevalence in the whole population (p = 3.1 × 10−21), this association was of greater magnitude (OR: 2.26; 95% CI: 1.84–2.78 for TT compared to CC homozygotes; p = 1.6 × 10−14) in non-obese (n = 3739) than in obese (n = 3279) subjects (OR: 1.51; 95% CI: 1.22–1.92 for TT compared to CC homozygotes; p = 0.0002) even after multivariable adjustment (Table 2).