Multivariate analyses confirmed that presence of diabetes and renal failure was independently associated with higher [Met(O)]/[Met] values of serum albumin (Met-111) (β = 0.368, F = 13.893, P < 0.001; β = 0.269, F = 7.180, P = 0.0095, respectively) and albumin (Met-147) (β = 0.589, F = 24.942, P < 0.001; β = 0.375, F = 13.551, P < 0.001, respectively) and that diabetes and smoking significantly impacted higher [Met(O)]/[Met] levels of Igγ1 chain C region (Met-135) (β = 0.601, F = 25.376, P < 0.001) and serum albumin (Met-147) (β = 0.281, F = 6.715, P = 0.012), respectively. This evidence concerns the gene ALB and Renal insufficiency.