COMP and pancreatic serous cystadenoma: Chandranet al. 35 found that levels of osteoprotegerin, high-sensitivity C-reactive protein (hs-CRP), cartilage oligomeric matrix protein (COMP), matrix metalloproteinase 3 (MMP-3), and the ratio of C-propeptide of type II collagen (CPII) to collagen fragment neoepitopes Col2-3/4 (C2C ratio) were higher in patients with PsA versus PsC.