The patient reported a personal history of chronic hepatitis C treated with pegylated interferon and ribavirin 16 years before and no particular familial history.Laboratory tests were within normal ranges, except for an elevated alkaline phosphatase of 158 u/l (normal range <104 U/L), a moderate hepatic cytolysis with a small elevation of transaminases, alanine transaminase (ALT) of 36 U/L (normal range 5-21 U/L) and aspartate transaminase (AST) of 37 U/L (normal range 5-30 U/L ) and increased carcinoembryonic antigen of 9.75 ng/mL (normal range for non-smokers < 3 ng/ mL). The gene discussed is GPT; the disease is chronic hepatitis C virus infection.