Most recently, biologic agents such as cetuximab/panitumumab (monoclonal antibodies directed against the epidermal growth factor receptor, EGFR) and bevacizumab (a humanized monoclonal antibody that targets vascular endothelial growth factor) have been proven to have therapeutic benefits in CRC alone or in association with standard chemotherapy [16]. Here, EGFR is linked to colorectal carcinoma.