IL10 and neoplasm: Indeed, 20% of these Tetramer+ cells expressed PD-1 in tumor-draining lymph nodes whereas these values increased to 80% in tumor infiltrating T lymphocytes (Supplementary Figure S8), supporting that in vivo, similarly to IL-10 blockade, inhibition of PD-1/PD-L1 axis would enhance vaccine-induced antitumor T cell responses.