CD274 and neoplasm: Then we included the variables including age, gender, laterality, tumor grade, clinical stage, tumor stage, metastasis, and PD-L1 mRNA level into a multivariate Cox regression model and found that PD-L1 mRNA level was an independent predictor for overall survival status of KIRC patients (HR=0.7, 95% CI 0.5-0.9, p=0.007; Table 2).