In one series of 45 samples of previously treated IBC samples immunohistochemical analysis showed activated JAK2 (pJAK2) levels were similar between IBC (95.2%, 1+ or 2+) and treated IDC (91.7%, 1+ or 2+; 4.2%, 3+), untreated IDC had lower levels (80.0%, 0; 20.0%, 1+) (p < 0.0001). Here, JAK2 is linked to inflammatory breast carcinoma.