ART4 and Epstein-Barr virus infection: Surprisingly, sera from mice immunized with a combination of two VLPs (gH/gL-EBNA1 and gB-LMP2, gH/gL-EBNA1 and gp350/220, or gB-LMP2 and gp350/220), or with all three VLPs, did not significantly reduce EBV infection compared to the single glycoprotein immunogens, in either of the cell lines used.