Compared to BS patients without thrombosis (Th−), BS patients with a history of thrombosis (Th+) had a significantly increased absolute number of MP (p < 0.0001; Fig. 5A), as well as increased TF+, CD14/TF+, and CD66b/TF+ MP counts (Fig. 5B,D,E,G) and percentages (Fig. 5C,E,G), MP numbers were found to be increased in male compared to female BS patients, and this was shown to be due to males having a greater number of Th+ patients (Supplementary Figures 5 and 6). This evidence concerns the gene TH and Bloom syndrome.