and is currently being developed by the U.S. Army for chemoprophylaxis of all malaria and by GlaxoSmithKline and Medicines for Malaria Venture for the radical cure of P. vivax. [5, 6] PQ and TQ are generally well tolerated, but there are known liabilities associated with hemolytic reactions in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiencies [2, 6–10]. Here, G6PD is linked to malaria.