CD14 and type 1 diabetes mellitus: As an example, FAIRE-seq in the K562 cell line shows significant read enrichment (t-test statistics 6.03, p value < 10–8) around risk variants associated with type 1 diabetes compared to benign ones, while H3K9me3 in the CD14 cell line shows significant read depletion around risk variants (t-test statistics –6.65, p value < 10–10) (Fig. 2b).