Noticeably, srGAP1 expression in CRCs was significantly correlated with tumor differentiation (Spearman r = −0.162, P = 0.044), lymphatic invasion (Spearman r = −0.194, P = 0.015) and TNM stage (Spearman r = −0.202, P = 0.011), suggesting that srGAP1 expression was associated with tumor progression. This evidence concerns the gene SRGAP1 and neoplasm.