Similarly, the capacity of AM or neutrophils to kill intracellular bacteria at 90 and 120 minutes post-infection was comparable between groups, demonstrating that basic antibacterial features of AM and neutrophils including oxidative burst (S4 Fig), phagocytosis and killing of pneumococci (S6 Fig) is not dependent on the presence of Mincle. This evidence concerns the gene CLEC4E and infection.