Similarly, we found that neutrophils collected by bronchoalveolar lavage from the lungs of patients with confirmed pneumococcal pneumonia also exhibited significantly upregulated Mincle gene expression, relative to peripheral blood neutrophils of the same patients (Fig 1C), demonstrating similar induction of Mincle gene expression in mice and humans in response to pneumococcal pneumonia. The gene discussed is CLEC4E; the disease is pneumococcal pneumonia.