IL37 and myocardial infarction: Our data were consistent with prior studies showing that restricting the acute inflammatory response attenuated ventricular remodeling.35, 40, 41 Several other studies have revealed similar observations that IL‐37 limited local inflammatory responses by inhibiting recruitment of inflammatory cells.17, 18, 42 Hence, we speculate that downregulation of the accumulation of neutrophils, macrophages, and lymphocytes by IL‐37 may be the potential mechanism for the protective influence of IL‐37 on post‐MI remodeling.