A clone survival assay showed that knockout of TNFAIP3 markedly decreased radiosensitivity in the NPC cells [AUC 2.73 (CNE1.siRNA) vs. 2.35 (CNE1.NC), RPF = 1.17 AUC 2.43 (CNE2.siRNA) vs. 2.07 (CNE2.NC), RPF = 1.17; p < 0.05] (Fig. 7a and b). This evidence concerns the gene TNFAIP3 and nasopharyngeal carcinoma.