Besides, 8 studies5, 14, 16, 17, 19, 23, 25, 28 examined the association of MTDH with distant metastasis and 12 studies5, 7, 8, 15, 16, 17, 19, 23, 25, 26, 27, 28 examined the association of MTDH with lymph node metastasis. The gene discussed is MTDH; the disease is metastatic malignant neoplasm in the lymph nodes.