A total of 8 studies6, 8, 16, 20, 23, 25, 27, 28 evaluated the relevance of MTDH expression with DFS in female reproduction cancers, with the overall random effects HR of 2.917(95% CI: 1.715–4.963, P < 0.001) (Fig. S1B, Table 3). Here, MTDH is linked to cancer.