For this we used oeSCN4B and shSCN4B cells as models of cancer cells, coming from the same lineage and solely differing by the presence of high levels of SCN4B/β4 protein (similar to non-cancerous mammary cells, oeSCN4B cells) or the complete absence of SCN4B/β4 protein (similar to high-grade cancers, shSCN4B cells). This evidence concerns the gene SCN4B and cancer.