HMOX1 and schizophrenia: Further supporting the concept that miR-7 regulates α-synuclein expression in vivo, Song et al. (2012) reported that schizophrenia-like transgenic mice overexpressing heme oxygenas-1 (HO-1) protein in astrocytes exhibited decreased levels of miR-7 and increased α-synuclein levels in the SN/ventral tegmental area (VTA) at 48-weeks of age compare to control animals.