The discovery that SNPs located within the miR-433 binding sites in FGF20 gene were associated with PD (van der Walt et al., 2004; Haghnejad et al., 2015) triggered two studies to investigate the potential impact of miR-433 in α-synuclein expression (Wang et al., 2008; Schmitt et al., 2012). This evidence concerns the gene FGF20 and Parkinson disease.