Depletion of C/EBPβ enhances TGF-β-induced EMT by decreasing the transcription of E-cadherin and of the coxsackie virus and adenovirus receptor, contributes to evasion of the growth-inhibitory effect of TGF-β, and further enhances invasion and metastatic dissemination of the mouse mammary tumor cells to the lungs after subcutaneous injection into mice [32]. The gene discussed is TGFB1; the disease is breast cancer.