According to our analysis above, the difference between YN13 and YN144 in replication ability might be due to the difference between the two PEDV-infection groups in alterations of eIF4G1, hnRNPA1, HSP90B1, HSP90AB1, HSPA8, DNAJA1, and DNAJC10 in jejunums of pigs. This evidence concerns the gene HSPA8 and infection.