Recently, we observed that, in chronic myeloid leukemia (CML), a myeloproliferative disorder sustained by the t(9:22) translocation coding for the chimeric protein BCR-ABL [82,83], the IκB-α protein is highly expressed in the cytoplasm [84]. Here, NFKBIA is linked to chronic myelogenous leukemia, BCR-ABL1 positive.