Genes differently expressed in CD34-positive chronic myeloid leukemia cells (Graham et al., 2007), in leukemia stem cells (Saito et al., 2010), in hematopoietic stem cells (Eppert et al., 2011, Georgantas et al., 2004), as well as in pediatric ALL cells with high risk of relapse (Kang et al., 2010) were all significantly enriched in LRC versus non-LRC cells (Figures 7D, S7B, and S7C). This evidence concerns the gene CD34 and acute lymphoblastic leukemia.