Interestingly, Plasmodium yoelii L3 ribosomal protein was recently identified as an antigenic target of memory CTLs induced by immunization with RAS, genetically attenuated parasites, and wildtype sporozoites with chloroquine prophylaxis, indicating that ribosomal proteins can be important targets of malaria specific CD8+ T cells [58]. This evidence concerns the gene CD8A and malaria.