To determine the effects of Sema3E on the functions of pancreatic cancer cells, we generated stable Sema3E-overexpressing and corresponding vector control cell lines via transduction of MiaPaCa-2 and Panc-48 cells with a lentiviral vector coding for Sema3E cDNA (-S3E) or vector control (-VCtrl). The gene discussed is SEMA3E; the disease is familial pancreatic carcinoma.