AGTR1 and hypertensive disorder: Ji et al. 7 also reported a significant association between AGTR1 rs275645 and hypertension; similarly, in our study, we found that the AGTR1 rs275645 GG genotype may reduce the risk for PE compared to the GA genotype (p = 0.0082, adOR = 0.174, 99% CI: 0.032, 0.957).