ACE and hypertensive disorder: Ji et al. 7 studied 41 tagSNPs in RAAS and found that the occurrence of hypertension among the Chinese Han population was associated with angiotensinogen (AGT) rs3789678 and rs2493132, angiotensin converting enzyme (ACE) rs4305, and angiotensin II receptor type 1 (AGTR1) rs275645.