Of the L-type calcium channel α1 subunits, expression of CACNA1D, CACNA1S, but not CACNA1C, was detected in MDA-MB-231 cells at the mRNA level (Fig. 3a; CACNA1F was not tested as it appeared to be often downregulated in breast cancer clinical samples). The gene discussed is CACNA1D; the disease is breast carcinoma.