SHPRH and Fanconi anemia: While there are a lack of Fanconi anemia functional homologs in yeast, our studies confirmed a requirement for RAD5, RAD18, and RAD51, genes identified as factors in the Fanconi-like crosslink pathway in yeast (Daee and Myung, 2012), in FA tolerance—suggesting HR repair may be mediated by the Fanconi-like pathway in response to FA in yeast.