Coincidently, several genome-wide studies from individuals with autism identify UBE3A as an autism-risk gene (Nurmi et al., 2001; Glessner et al., 2009; Schaaf et al., 2011; Kelleher et al., 2012; Carvill et al., 2013; Iossifov et al., 2014; Yuen et al., 2015). This evidence concerns the gene UBE3A and autism.