In contrast, mixed bone marrow chimeras lacking functional GM-CSFR in one donor population showed that equal numbers of Mo-DCs from WT and Csf2r-/- mice were present in the inflamed central nervous system (CNS) in experimental autoimmune encephalomyelitis [3]; similarly, monocytes from WT and Csf2r-/-Csf2rb2-/- mice were able to differentiate into Mo-DCs in equal numbers in the lungs and lung-draining lymph nodes when adoptively transferred intravenously into mice infected intranasally with influenza virus [3]. Here, CSF2RBP1 is linked to experimental autoimmune encephalomyelitis.