EGFR and non-small cell lung carcinoma: Since the EGFR mutational status may confound attempts to address whether AS therapy adversely impacts PFS and OS in erlotinib or gefitinib-treated NSCLC patients, we performed a retrospective study examining a consecutive series of patients who tested positive for known activating EGFR mutations, who received EGFR TKIs with or without concomitant AS therapy.