However, the tumor samples of the two ovarian cancer patients were analyzed for the presence of pathogenic variants in the coding regions of the 29 genes involved in DNA repair (ATM, ATR, BLM, BRIP1, CHEK1, CHEK2, ERCC1, FANCA, FANCC, FANCD2, FANCF, MLH1, MRE11A, MSH2, MSH6, PALB2, PER1, PMS1, PMS2, PRKDC, PTEN, RAD50, RECQL4, SMUG1, TP53, WRN, XPA, XPC, and XRCC2). The gene discussed is CHEK2; the disease is ovarian cancer.