Effector ATCs generated from healthy donors stimulated with samples from patients with AML in vitro for 4 hours showed an increased expression of the CD8+ T-cell degranulation marker CD107a, with a 4.7±1.5-fold increase for CAR.CD33 as compared with NT (N = 8), and a 5.4±1.7-fold increase for ΔCD19 sel. Here, CD8A is linked to acute myeloid leukemia.