However, there was no significant difference in the expressions of PPP3CB (14.66±0.38 vs. 13.28±0.02, P = 0.167), PPP3R1 (14.29±0.41 vs. 16.16±0.91, P = 0.052), PLCE1 (15.95±0.46 vs. 14.22±0.02, P = 0.167), MEF2C (15.99±0.58 vs. 14.46±1.47, P = 0.392) and CAMK1 (18.49±0.29 vs. 18.86±0.38, P = 0.484) between MR patients with renin-angiotensin system blockers (n = 11) vs. MR patients without renin-angiotensin system blockers (n = 3). This evidence concerns the gene MEF2C and miotic rate.