LATS2 and non-small cell lung carcinoma: It was also reported that the upregulation of the long non-coding RNA AGAP2-AS1 facilitates cell proliferation, migration and invasion, and inhibits cell apoptosis; it also represses LATS2 and KLF2 expression through its interaction with EZH2 and LSD1 in non-small-cell lung cancer cells [35].