Even in patients with FLT3-mutated leukemia, a number of small molecule tyrosine kinase inhibitors with activity against FLT3 have been developed [22, 23] but, as of yet, none of the studied FLT3 inhibitors has not been used for routine clinical use in FLT3-mutated AML. The gene discussed is FLT3; the disease is acute myeloid leukemia.