TGFβ primes LM2 cancer cells forpulmonary metastasis seeding via Angiopoietin-like potein 4(ANGPTL4).3 The basal andTGFβ-induced ANGPTL4 mRNA levels were remarkablyreduced in Bcl-3 depleted MDA-MB-231 and LM2 cells compared with controlcells (Figure 4e). The gene discussed is TGFB1; the disease is cancer.