INTU and cancer: Similarly, the presence of EpCAMposCD49fpos (CLPs) subsets of cells in luminal A and B breast cancer cell lines and tissues were reported previously.15 Interestingly, Int-αvβ3 re-expression in luminal A breast cancer cell lines did not expand the CSCs population as was reported for other types of cancers,34 thus suggesting that Int-αvβ3 diverse effect depends on cancer type and subtype.