Incubating isolated neutrophils with sera from TP who developed pneumonia showed significantly decreased CD11b expression over the time course compared to the corresponding group of TP without pneumonia (ED: 83.46 ± 9.99 MFU vs. 113.9 ± 15.41 MFU, one day prior infection: 104.1 ± 18.4 MFU vs. 152.6 ± 23.29 MFU, and day of infection: 91.64 ± 14.94 MFU vs. 155.7 ± 26.14 MFU, all p < 0.05, Fig. 2). Here, ITGAM is linked to infection.