PNPLA3 and metabolic dysfunction-associated steatotic liver disease: The results revealed that the G-allele number of the PNPLA3 rs738409 polymorphism interacted with physical activity on childhood NAFLD significantly (OR 3.13, 95% CI 1.57–6.24, P = 0.001), and also with sedentary behavior (OR 2.47, 95% CI 1.25–4.91, P = 0.010), and further with the combination of the two factors (OR 6.11, 95% CI 2.79–13.37, P < 0.001).