GGCT and urinary bladder carcinoma: Furthermore, it has beenproved thatGGCTfunctioned as a novel biomarker of esophageal squamous malignancies, as its expression levels strongly correlated with lymph node metastasis and differentiation degree [6–11], in consistent with that overexpression and depletion of GGCT resulted in proliferative and antiproliferative activities in bladder cancer cells, respectively [9].