As shown in Fig. 2A, EMR2 expression on neutrophils increased significantly in cirrhotic patients with infectious complications than cirrhotic patients without infectious complications (MFI of EMR2: cirrhotic patients with infections vs. cirrhotic patients without infection: 44.40 ± 26.05 vs. 26.73 ± 13.03, p < 0.001). This evidence concerns the gene ADGRE2 and infection.