To confirm whether chemo-sensitivity score was an independent risk factor for OS in TCGA CN-AML patients, association between the score and some known risk factors for AML outcome, including cytogenetic risk, NPM1 mutations, FLT3-IDT mutations, CEBPA mutations, IDH mutations, and DMNT3A R882 mutations were analyzed. The gene discussed is NPM1; the disease is acute myeloid leukemia.