Oncoprints showed alterations (amplification, gain, shallow deletion, mRNA upregulation and mRNA downregulation) of RAC1 gene in multiple subtypes of BC from two data sets, (1) TCGA, Nature, 2012 (cBioPortal) and (2) TCGA, Cell 2015; brca/tcga/pub2015 (cBioPortal) (Figure 1A-1C). This evidence concerns the gene RAC1 and breast cancer.