In bladder cancer, such genes as SETDB1 on human chromosomal region 1q21, FGFR1 on 8p12, MDM2 on 12q13, E2F3, CDKAL1, SOX4, MBOAT1, NUP153, AOF1, FAM8A1, and DEK on 6p22, CCND1 on 11q13, and CCNE1 and BCL2L1 on 20q11 are amplified, while the CDKN2A gene located on chromosomal region 9p21.3 is deleted [19, 20, 22]. The gene discussed is MDM2; the disease is urinary bladder cancer.