The results indicate that 4 out of 113 of bladder cancer samples (3.54%) had copy number gain, and 2 of them (50%) demonstrated CYP2A6 overexpression, suggesting that CYP2A6 protein levels may be regulated by other mechanisms at the transcriptional, translational, or epigenetic levels. Here, CYP2A6 is linked to urinary bladder carcinoma.