Intraductal papillary mucinous neoplasm (IPMN) of the pancreas is an exocrine tumor composed of intraductal papillary growth of mucin containing neoplastic cells in the main pancreatic duct or its branches.[1] IPMN encompasses a wide spectrum that ranges from adenomas to invasive cancer with various degrees of aggressiveness.[2] Infrequently, IPMN can invade into the adjoining organs including duodenum (59–64%), common bile duct (CBD) (51–57%), and stomach (17%).[3]. The gene discussed is MUC5AC; the disease is pancreatic intraductal papillary-mucinous neoplasm.