The concentration of CRP, a plasma protein, rises dramatically as a result of cytokine-mediated responses to most forms of infection, inflammation, and tissue injury.[27] In this study, serum CRP was not significantly different between the NSG and SG, as was found in the study of Kittaka et al.[9] Also, Simon et al reported that, for bacterial infections, serum CRP has little sensitivity and specificity.[28] We feel that further study is needed to determine the usefulness of CRP in this regard. This evidence concerns the gene CRP and bacterial infectious disease.