Altered levels of cytokines and growth factors and their corresponding receptors, such as transforming growth factor alfa and beta protein families, epidermal growth factor, fibroblast growth factor family, bone morphogenetic protein 4 and interleukin 6 (IL-6)/glycoprotein 130 family, has been observed in pituitary tumors [21–24]. Here, IL6 is linked to pituitary tumor.