MAPK8 and lung cancer: We further examined substrates of other key cancer cell signaling pathways, including P-AKT (S473), P-ERK (T202/Y204), P-C-JUN (S63) and P-MK2 (T334), but no correlation between expression of these proteins and Rab1A expression was observed (Figure 2C-G), indicating that, under physiological conditions, Rab1A expression is not correlated with the basal expression levels of the mTORC1, mTORC2, MEK, JNK and p38MAPK signaling pathways in lung cancer.